The key to victory with Miami is simple. You have to take Wade out.

I don't mean actually intentionally try to hurt him. Just give him a good hard foul every time he drives. Prince can overplay his 10-15 foot jumper and then the bigs (Use Davis and Cato and others early in the game and early in the series) can hammer him (legally) when he comes inside. Wade only has one game, and that's all out going to the rim. If you aggressively defend the goal he'll either settle for jumpers, or bang himself up trying to get to the rim. Actually I think that if he doesn't develop a great outside shot soon (ala Jordan), his career will be pretty short. Guys who recklessly drive to the hole get injured a lot and their atheleticism slowly decreases as years go by.